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Correlation of Ophthalmic Artery Pulsatility Index with Systolic, Diastolic and Mean Arterial Pressure in Normotensive and Hypertensive Pregnancies: A Cross-sectional Study |
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Subha Metya, Sahil Goyal, Manish Madan, Soumit Roy 1. Postgraduate Trainee, Department of Radiology, IQ City Medical College and Hospital, Durgapur, West Bengal, India. 2. Postgraduate Trainee, Department of Radiology, IQ City Medical College and Hospital, Durgapur, West Bengal, India. 3. Professor, Department of Radiology, IQ City Medical College and Hospital, Durgapur, West Bengal, India. 4. Assistant Professor, Department of Community Medicine, IQ City Medical College and Hospital, Durgapur, West Bengal, India. |
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Correspondence Address : Subha Metya, MD5, 9F, IQ City Residential Complex, Durgapur-713206, West Bengal, India. E-mail: subhametya007@gmail.com |
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| ABSTRACT |  | ||||||
: Introduction: Hypertensive disorders complicate 5-15% of pregnancies and are major contributors to maternal and neonatal morbidity and mortality, particularly in cases involving preeclampsia. Affecting approximately 3% of pregnancies, preeclampsia is linked to complications such as preterm birth and low birth weight and is often associated with ocular changes in 30-100% of cases, marked by altered orbital vascular resistance. Traditional blood pressure measurements, while essential, may not fully capture vascular changes, especially in microcirculation, during hypertensive pregnancies. Doppler ultrasonography of the Ophthalmic Artery (OA) provides a non invasive method for assessing these vascular changes. The Ophthalmic Artery Pulsatility Index (OAPI) serves as a measure of vascular resistance in the OA, offering potential as a marker for evaluating and monitoring hypertensive disorders in pregnancy. Aim: To compare OAPI values between normotensive and hypertensive pregnant women and to analyse the correlation between OAPI and maternal blood pressure parameters. Materials and Methods: This cross-sectional study was conducted in the Department of Radiology, IQ City Medical College and Hospital, Durgapur, West Bengal, India, from January to August 2023. Systematic random sampling was used to divide participants into three groups: 50 normotensive non pregnant women, 50 normotensive pregnant women and 50 hypertensive pregnant women. The hypertensive group was further subdivided into mild preeclampsia (n=18), severe preeclampsia (n=12), gestational hypertension (n=10) and chronic hypertension (n=10). Doppler ultrasonography was used to measure OAPI and blood pressure parameters, including Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP) and Mean Arterial Pressure (MAP), were recorded. Data analysis employed the Kruskal-Wallis test to compare OAPI values across groups and Spearman’s rho correlation was used to assess relationships between OAPI and blood pressure parameters, with statistical significance set at p<0.05. Results: The mean age of the subjects was 26.6±5.6 years. The OAPI was notably lower in the hypertensive group at 1.5±0.3, compared to 2.27±0.15 in the normotensive pregnant group and 2.17±0.08 in the normotensive non pregnant group (p<0.05). Within the severe preeclampsia subgroup, the mean OAPI was 1.17±0.14, indicating the highest level of vascular resistance. Strong negative correlations were found between OAPI and blood pressure parameters, with Spearman’s rho values of ρ=-0.731 (p<0.01) for SBP and ρ=-0.774 (p<0.01) for MAP. Conclusion: The OAPI proves to be a valuable non invasive marker for detecting and monitoring hypertensive disorders in pregnancy. Its significant inverse correlation with blood pressure parameters highlights its potential for early diagnosis and effective management of hypertensive conditions, particularly severe preeclampsia. | |||||||
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| Keywords : Doppler ultrasonography, Hypertensive disorders in pregnancy, Preeclampsia | |||||||
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DOI and Others :
DOI: 10.7860/IJARS/2025/76149.3031
Date of Submission: Oct 09, 2024 Date of Peer Review: Nov 01, 2024 Date of Acceptance: Nov 21, 2024 Date of Publishing: Jan 01, 2025 AUTHOR DECLARATION: • Financial or Other Competing Interests: None • Was Ethics Committee Approval obtained for this study?Yes • Was informed consent obtained from the subjects involved in the study? Yes • For any images presented appropriate consent has been obtained from the subjects. Yes PLAGIARISM CHECKING METHODS: • Plagiarism X-checker: Oct 10, 2024 • Manual Googling: Nov 12, 2024 • iThenticate Software: Nov 20, 2024 (10%) ETYMOLOGY: Author Origin EMENDATIONS: 6 |
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