|
|
|
Year :2026
|
Month :
March-April
|
Volume :
15
|
Issue :
2
|
Page :
RO09 - RO12
|
Association of Pituitary Gland Volume in Adults with Body Mass Index: A Cross-sectional Study
|
Correspondence Address :
Lakshman Suryaa, R Mithunraj, Selva Micheal Papou, Palle Manjunatha Reddy, Nithin Joe Theckumparampil,
Dr R Mithunraj
Pondicherry Institute of Medical Sciences, Ganapathychettykulam,
Puducherry, India.
E-mail: dr.muthu1211@gmail.com
|
|
Introduction: Introduction: The pituitary gland is central to endocrine regulation influencing growth, metabolism, and reproduction. Magnetic Resonance Imaging (MRI) provides a reliable non-invasive method for assessing pituitary morphology. Variations in pituitary volume have been reported in relation to age, sex, and body stature and Body Mass Index (BMI).
Aim: To estimate pituitary gland volume using MRI and analyse its correlation with BMI.
Materials and Methods: The present cross-sectional study was conducted on 285 adults (18-85 years) undergoing MRI for non-endocrine neurological indications in the Department of Radiodiagnosis, Institute of Medical Sciences, Puducherry, India, from May 2023 to May 2025. Pituitary dimensions {Antero-Posterior (AP), Cranio-Caudal (CC) and Transverse (TR)} were measured on standardised T1 and T2-weighted images, and volume was calculated using ellipsoid formula. Demographic data (age, sex, height, weight, BMI) were recorded. Correlation and comparative analyses were performed.
Results: The mean pituitary volume was 532.3±166.2 mm3. Females (560±168.4 mm3) had a higher mean pituitary volume than males (512±162.7 mm3); however, the difference did not reach statistical significance (p=0.08). Pituitary volume showed a strong positive correlation with BMI (r=0.715, p<0.001) and body weight (r=0.762, p<0.001). Age demonstrated a negative correlation with gland volume (r=-0.234, p<0.001).
Conclusion: MRI-based volumetry of the pituitary gland reliably reflects its association with BMI. BMI emerged as the strongest determinant of pituitary size, while age showed an inverse effect.
|
|
|
[
FULL TEXT ] | [
 ]
|
|
|
|
|