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Original article / research

2026
Year :2026 Month : July-August Volume : 15 Issue : 4 Page : RS04 - RS06

MR Characteristics of Prostate Stromal Sarcoma: A Series of Four Cases

Published: July 1, 2026 | DOI: https://doi.org/10.7860/JCDR/2026/87654.3111
Correspondence Address :
Madhuri Nandu, Pragya Surolia, Mayank Choudhary, Narendra Kumar Kardam, Kushal Babu Gehlot,
Madhuri Nandu,
Room No 411, SR Building, Dilshad Bhavan, Udaipur-313001, Rajasthan, India.
E-mail: madhuricharan1197@gmail.com
Introduction: Prostate stromal sarcoma is a rare neoplasm arising from the stromal component of the prostate. The clinical symptoms of prostatic sarcoma and prostatic adenocarcinoma are similar. It differs from more common prostatic adenocarcinoma in terms of age of presentation, biological behaviour, and imaging appearance. Magnetic Resonance Imaging (MRI), including Diffusion-Weighted Imaging (DWI), is the modality of choice for lesion characterisation, assessment of local extent, and surgical planning. We are presenting a case series of four patients presenting with lower urinary tract symptoms, including urinary urgency, frequency, dysuria, and pelvic pain, all of whom had normal serum Prostate-Specific Antigen (PSA) levels. MRI demonstrated a large T2-weighted hyperintense mass with internal cystic changes and marked diffusion restriction on DWI. The lesion appeared predominantly well-defined, with areas of heterogeneity corresponding to cystic or necrotic components. On Apparent Diffusion Coefficient (ADC) maps, these regions showed low signal intensity, consistent with true diffusion restriction, suggestive of high cellularity.
 
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